Bo and Luke Duke are southern cousins. In Hazzard County, Bo and Luke help their Uncle Jesse and their sexy cousin Daisy run the Moonshine business and always getting into trouble with Sherriff Roscoe P. Coltrane and recklessly driving in their orange car "General Lee". Boss Hogg, the mean and corrupt local county commissioner who hates The Dukes evicts The Dukes from their farm. Bo and Duke travels to Atlanta and meets up with old friend Katie Johnson and her friend Annette as they set out to find out why Boss Hogg has evicted them from their farm and what he plans to do. With local ace race car driver Billy Prickett in town to take part in the Annual Hazzard Road Race rally, Bo and Luke sets out to save their farm and foil Boss Hogg's scheme.

After moving to the country to start life anew after their child's death, photographer Shawn Burnett and his wife, Helen, begin to suspect that a ramshackle cabin on their property is haunted by the malevolent spirit of a long-dead witch who once lived there.